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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK7
All Species:
21.21
Human Site:
T420
Identified Species:
35.9
UniProt:
Q8WTQ7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTQ7
NP_631948.1
553
62212
T420
K
F
Q
H
D
N
F
T
E
E
A
K
D
I
C
Chimpanzee
Pan troglodytes
XP_526333
553
62171
T420
K
F
Q
H
D
N
F
T
E
E
A
K
D
I
C
Rhesus Macaque
Macaca mulatta
XP_001112570
553
62224
T420
K
F
Q
H
D
N
F
T
E
E
A
K
D
I
C
Dog
Lupus familis
XP_542813
553
62196
T420
Q
F
Q
H
D
N
F
T
E
E
A
K
D
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEB1
590
67714
E415
Y
S
S
K
F
S
E
E
A
K
S
I
C
N
M
Rat
Rattus norvegicus
Q62833
590
67764
E415
Y
S
P
K
F
S
E
E
A
K
S
I
C
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
R421
K
Y
P
E
K
F
S
R
A
S
K
D
F
C
E
Chicken
Gallus gallus
XP_426681
551
62925
T416
K
F
E
H
A
N
F
T
E
E
T
K
D
I
C
Frog
Xenopus laevis
NP_001131051
551
62674
T417
V
F
Q
H
P
V
F
T
E
E
A
K
D
I
C
Zebra Danio
Brachydanio rerio
NP_001027011
549
62214
N415
E
P
K
F
E
H
K
N
F
D
A
A
T
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
E539
Y
S
S
K
F
N
D
E
A
K
S
M
C
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
A432
Y
S
E
K
F
S
E
A
A
R
T
L
C
R
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42818
465
52569
L349
I
V
K
D
K
I
K
L
P
Q
F
L
S
N
E
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
R641
D
V
L
S
Q
E
G
R
S
F
V
K
G
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.9
85.7
N.A.
41.8
42.2
N.A.
47.9
72.8
68.7
60.2
N.A.
38.2
N.A.
39.4
N.A.
Protein Similarity:
100
99.4
98
92.7
N.A.
60.6
60.6
N.A.
65.8
84.2
82.8
75.9
N.A.
54.3
N.A.
57.6
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
6.6
80
80
13.3
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
13.3
86.6
80
46.6
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
36
0
43
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
29
8
43
% C
% Asp:
8
0
0
8
29
0
8
0
0
8
0
8
43
0
8
% D
% Glu:
8
0
15
8
8
8
22
22
43
43
0
0
0
0
15
% E
% Phe:
0
43
0
8
29
8
43
0
8
8
8
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
43
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
0
15
0
50
0
% I
% Lys:
36
0
15
29
15
0
15
0
0
22
8
50
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
8
0
0
0
15
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
15
% M
% Asn:
0
0
0
0
0
43
0
8
0
0
0
0
0
22
0
% N
% Pro:
0
8
15
0
8
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
0
36
0
8
0
0
0
0
8
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
15
0
8
0
0
0
8
0
% R
% Ser:
0
29
15
8
0
22
8
0
8
8
22
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
43
0
0
15
0
8
0
0
% T
% Val:
8
15
0
0
0
8
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
29
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _